Remy "Thirteen" Hadley, M.D., is a fictional character on the Fox medical drama House. She is portrayed by Olivia Wilde. She is part of the new diagnostic team assembled by Dr.
Gregory House after the disbanding of his previous team in the third season finale. The character's nickname derives from the episode "The Right Stuff", when she was assigned the number during a competition for her position at the Princeton-Plainsboro Teaching Hospital. The show depicts Thirteen as a secretive character who does not divulge personal information; her surname was not used on the show until the fourth season finale "House's Head", nor her given name until the fifth season episode "Emancipation".
Instead, several of the character's traits are implied before they are depicted as true. In the season four episode "You Don't Want to Know", Thirteen tells Dr. House that her mother died from Huntington's disease; a test she performs several episodes later confirms she carries the gene.
After hints were given regarding her character's sexuality, actress Olivia Wilde revealed that her character is indeed bisexual, a fact that is pivotal to the plot of the episode "Lucky Thirteen". Thirteen is reluctant to reveal information about herself, creating an air of mystery about her. Early on, House tries to guess what her big secret might be, such as asking if she was the "daughter of an alcoholic father", she responds with "wrong again".
In "Mirror Mirror", a patient who mirrors the most dominant personality present describes himself as "scared" when alone with her. She hints her secret in the eighth episode of the fourth season, "You Don't Want to Know", when she tells House that her mother died from Huntington's disease, but she does not wish to know if she carries the gene. Not knowing, she explains, allows her to summon the bravery to do things she thinks she cannot do.
House surreptitiously obtains a sample of her DNA and has the screening performed, but in the end throws out the unopened envelope containing the results. The season four finale reveals that she does indeed have the dominant mutation for Huntington's. In the fifth episode of the fifth season, "Lucky Thirteen", Thirteen mentions that her Huntington's is more aggressive because the generation that received the gene has more repeats of the CAG triplet of the previous generation, decreasing her lifespan and hastening the onset of symptoms.
Despairing, she exhibits self-destructive behavior, using recreational drugs and having repeated one-night stands with women. House fires her for recklessness but later rehires her, using the circumstance to test if she would grow close with a terminal patient. When the patient's diagnosis changed to a non-terminal affliction, Thirteen tells Eric Foreman, "I feel alone...and she hasn't gone anywhere." to which he replies, "She gets to live." Thirteen is later shown reverting to her self-destructive habits, which climaxes in the ninth episode "Last Resort" when she risks her life to test medication for a man who took the hospital clinic hostage.