Brian Keller Vaughan (born 1976, Cleveland, Ohio) is an American comic book and television writer. He is best known for the comic book series Y: The Last Man, Ex Machina, Runaways, and Pride of Baghdad, and as one of the principal writers of the television series Lost beginning with its third season. He was nominated for a Writers Guild of America Award for Best Dramatic Series at the February 2009 ceremony for his work on the fourth season of Lost.

As an undergraduate film student at New York University, Vaughan took part in Marvel's Stan-hattan Project, a class for fledgling comic book writers. His first credit was Cable #43 (May 1997). Vaughan has written most of the major DC and Marvel characters, including Batman and the X-Men.

He has also written several screenplays, stage plays, and short stories, although he prefers writing comic books. He has stated in an interview with Wizarduniverse.com that he prefers to write his own creations like Y: The Last Man and Ex Machina because he doesn't think he's the best at using his "voice" with company-owned characters.

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