Charlotte center city (also known as Uptown or Downtown Charlotte) is the area comprising the township and original city of Charlotte, North Carolina. Its numerical distinction within the county is 1 (of 15). Its official distinction would be Charlotte, Mecklenburg County, North Carolina.

Charlotte center city is also one of three Municipal Service Districts in Charlotte. The area, bounded by the John Belk and Brookshire Freeways (the I-277 loop), is further broken down into four wards. Of them, First, Third, and Fourth Wards have residential areas.

The Second Ward is made up primarily of city and county government offices. The residential population of the center city is approximately 10,000. By 2010, this number is expected to grow from 10,000 to 27,000 due to recent construction of multiple high rise condominium towers such as The Vue Charlotte, 300 South Tryon, The Catalyst, and many other skyscrapers that are currently under construction.

Uptown or Downtown is where Charlotte's business sector is located, largely made up of banking and other financial service industries. About 77,000 people work in Charlotte's center city. The headquarters for the Fortune 500 companies: Bank of America, Duke Energy, and Wachovia are located here, though it is not clear where the headquarters will be once the acquisition of Wachovia by Wells Fargo is complete.

Wachovia is currently building a major complex of towers that will contain three new art venues, a condominium tower, and a new office building, dubbed the Duke Energy Center, the top 20 floors of which are leased out to Duke Energy. Museums, sporting venues, hotels, restaurants, and bars are heavily concentrated in Uptown Charlotte as well. Many more hotels such as the Ritz Carlton, aLoft and museums such as the Betchler Art Museum and the new Mint Museum are expected to open before 2010.

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