Neosporin (from Neo, (Greek) new + Sporos, (Greek) seed) is the product name of an antibiotic ointment produced by Pfizer (later sold to Johnson & Johnson) used in the prevention of infection and speeding the healing of wounds. The original ointment contains three different antibiotics: bacitracin, neomycin, and polymyxin B. Other brand names for this mixture include Mycitracin and Topisporin.

The generic drug name for this mixture is "Triple antibiotic ointment". In China, this product is called "Complex Polymyxin B Ointment" which is manufactured by Zhejiang Reachall Pharmaceutical. GlaxoSmithKline manufactures Neosporin in many other countries, including Canada.

In Mexico, GSK's trade name "Neosporin Dermico" is used for the topical ointment. Some people have allergic reactions to neomycin, so a "Double antibiotic ointment" is sold that only contains bacitracin and polymyxin B (for example, product name Polysporin).

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