Alice Abernathy was a former Umbrella security officer-turned anti-Umbrella activist. Alice was once an Umbrella security operative placed at the mansion to protect the Hive's emergency entrance. Alice is married to Spence Parks, however, their marriage is revealed to be a fake, in order to cover the operation's secrecy.

After Alice's exposure to the T-virus via experimentation conducted by the Umbrella Corporation, the virus somehow bonded with her in a way that is not seen in others who are infected. In turn, the virus gave her enhanced senses, agility, speed, strength, and accelerated healing. By the end of Apocalypse, she develops telekinetic abilities by added experimentation.She is also able to dispatch most human foes with ease; during her time with the psychopaths in Extinction.

She gains all of the T-virus's "positive" effects and none of its negative effects. Alice was able to maintain her humanity and a strong sense of confidence in her skills as an advantage against even the most superior foes. As Alice confronts Wesker on a chopper after he has blown up his facility, he injects her with a serum that destroys the T-cells in her body from the virus and thus renders her powerless.

Alice actually thanks Wesker for this as it allows her to become a normal human again. Even without her powers, Alice retains the same level of confidence and fighting skills as she possessed with them before when she was a security operative of the Hive, and is even able to defeat an empowered Wesker (who had similar powers to her own) even without her powers, using her own cunning and skill. However near the end of Afterlife, it's shown that she is able to "read" the final moments of a captive through touching their holding tube, signifying that the effects of the t-virus may have not completely dissipated from her system.

It is unknown whether or not her abilities will return* .

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