Penn Station is a chain of East Coast sub restaurants found throughout the South and Midwest United States. The first restaurant was opened in 1985 by Jeff Osterfeld in Cincinnati, Ohio. Today, there are more than 200 Penn Station restaurants in the United States.

The concept for an East Coast sub restaurant came to Jeff Osterfeld soon after he graduated from Miami University in Oxford, Ohio. In 1983, he opened "Jeffrey's Delicatessen" at Dayton Mall in Dayton, Ohio. It was during a trip to Philadelphia that he first realized the popularity of the cheesesteak sandwich.

He began selling a version of the cheesesteak sandwich at his own restaurant, and it instantly became a huge hit. He eventually expanded to Cincinnati, where he opened his first Penn Station restaurant in 1985. Originally, only four sandwiches were available, including the cheese steak.

However, this first restaurant also offered fresh-cut french fries and freshly squeezed lemonade, two items that would become trademarks for Penn Station in the future.

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